• Nov 27, 2025 losartan potassium usp 36 monograph n. Metabolism: Losartan undergoes hepatic metabolism via CYP2C9 and CYP3A4 to produce an active metabolite, EXP3174, which has a potency approximately 10-40 times greater than the parent compound. Excretion: The drug and its metabolites are primarily eliminated via renal and biliary rou By Dave Cartwright
